Details

Project TitleHerpes Simplex Virus Glycoprotein H monoclonal antibody LP11 (anti-HSV gH)
Track CodeAB103
Websitewww.enterprise.cam.ac.uk
Short Description

Hybridoma cell line producing LP11 antibodies raised against Herpes Simplex Virus Type-1 envelope protein Glycoprotein H, which are mouse monoclonal antibodies of the IgG2a isotype. Strongly neutralises virus in the absence of Complement.  Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples.  Does not work in Western blots.  Produces antibodies with unique anti-gH neutralising properties.

AbstractNone
 
Tagsreagent, antibody, hybridoma, cell line
 
Posted DateMar 17, 2011 10:51 AM

Publications

Buckmaster EA, Cranage MP, McLean CS, Coombs RR, Minson A.  The use of monoclonal antibodies to differentiate isolates of herpes simplex types 1 and 2 by neutralisation and reverse passive haemagglutination tests. 
J Med Virol. 1984  13:193-202.
http://eu.wiley.com/WileyCDA/WileyTitle/productCd-JMV.html

Contact Information

Dr Emma Barker

reagents@enterprise.cam.ac.uk

tel: +44 (0)1223 760339   
Cambridge Enterprise Ltd.              
University of Cambridge           
Hauser Forum                                      
3 Charles Babbage Rd.   
Cambridge                                            
CB3 0GT                                                    
UK                
www.enterprise.cam.ac.uk

Commercialisation

We are seeking to establish non-exclusive relationships.